This Low Carb Chicken Casserole recipe is the perfect comfort food for anyone looking to maintain a healthy lifestyle without sacrificing flavor. Loaded with tender chicken, creamy cheese, and a medley of vegetables, this casserole is not only satisfying but also fits seamlessly into a low-carb diet. It’s a one-dish wonder that brings warmth to your dinner table and is sure to become a family favorite.

Why You Will Love This Recipe
Readers will adore this recipe for its incredible flavor profile and convenience. The combination of juicy chicken, rich cheese, and colorful veggies creates a delicious casserole that is both hearty and nutritious. This dish is easy to prepare, requiring minimal hands-on time, making it ideal for busy weeknights. Plus, with fewer carbs than traditional casseroles, it fits perfectly into any low-carb or keto lifestyle, allowing you to indulge without guilt.
Tips and Tricks
- Use Rotisserie Chicken: For a quicker version, use store-bought rotisserie chicken. Just shred it and mix it into the casserole base for a time-saving shortcut.
- Cheese Choices: Experiment with different types of cheese. Cheddar, mozzarella, or even pepper jack can add a unique twist to the flavor.
- Seasoning Boost: Don’t shy away from herbs and spices! Fresh thyme or Italian seasoning can elevate the dish. Add them to the mix for an extra layer of flavor.
- Veggie Variety: Feel free to swap in your favorite low-carb vegetables like bell peppers, zucchini, or spinach for added nutrients and flavor.
Make Ahead Tips
This casserole is excellent for meal prepping! You can prepare the mixture a day ahead and store it in the refrigerator before baking. Just cover it tightly with plastic wrap or foil. It will stay fresh for up to 24 hours. When ready to bake, simply remove it from the fridge, let it sit at room temperature for about 30 minutes, and then pop it in the oven.

Recipe Variations
- Spicy Version: Add diced jalapeños or red pepper flakes for a kick.
- Different Proteins: Swap chicken for ground turkey or beef for a different flavor profile.
- Vegetarian Option: Replace chicken with tofu or a hearty vegetable mix to create a satisfying vegetarian casserole.
- Cauliflower Rice: For an even lower-carb version, substitute rice with cauliflower rice for added texture without the carbs.
How to Serve
Serve this low carb chicken casserole straight from the oven for a rustic, homey feel. Garnish with freshly chopped parsley or chives for a pop of color. Pair it with a simple side salad dressed with olive oil and vinegar to balance the richness of the casserole. For a special touch, serve it in individual ramekins for a charming presentation.

Pairing Suggestions
For drink pairings, a crisp white wine like Sauvignon Blanc or a light-bodied red such as Pinot Noir complements the casserole beautifully. If you prefer non-alcoholic options, a sparkling water with a slice of lemon is refreshing. As for sides, consider serving a warm cauliflower mash or roasted asparagus to round out the meal.
How to Store
Leftovers can be stored in an airtight container in the refrigerator for up to 3-4 days. For longer storage, freeze the casserole in a freezer-safe container for up to 3 months. To reheat, thaw in the fridge overnight and bake in the oven at 350°F (175°C) until hot, about 25-30 minutes.
Equipment Needed
You will need a 9×13-inch baking dish or a similar casserole dish. A mixing bowl for combining ingredients and a cooking spray or oil for greasing the dish will also be needed. If you prefer, a slow cooker can be used for a hands-off approach.

Dietary Adaptations
For a vegan version, replace chicken with chickpeas or lentils and use plant-based cream and cheese alternatives. To make it dairy-free, use coconut cream and nutritional yeast for a cheesy flavor. Nut-free options can easily be achieved by avoiding any nut-based ingredients.
Seasonal Adaptations
In the spring and summer, incorporate fresh vegetables like zucchini, asparagus, or cherry tomatoes for a seasonal touch. In the fall and winter, consider adding root vegetables such as turnips or butternut squash for a heartier dish.
Recipe FAQs
- Can I substitute the chicken? Yes! Ground turkey or beef can be used, or for a vegetarian option, try tofu or legumes.
- How long does it take to cook? The casserole typically takes about 30-40 minutes in the oven after being assembled.
- Can I freeze leftovers? Yes! Leftovers can be frozen for up to 3 months. Just ensure you store them in a freezer-safe container.
How To Make low carb chicken casserole recipe
Low Carb Chicken Casserole

This Low Carb Chicken Casserole recipe is the perfect comfort food for anyone looking to maintain a healthy lifestyle without sacrificing flavor.
Ingredients
- 2 cups cooked chicken, shredded
- 1 cup broccoli florets
- 1 cup cauliflower florets
- 1 cup bell peppers, diced
- 1 cup shredded cheese (cheddar, mozzarella, or your choice)
- 1 cup heavy cream
- 2 cloves garlic, minced
- 1 teaspoon Italian seasoning
- Salt and pepper to taste
- Olive oil, for greasing
Instructions
- Preheat your oven to 350°F (175°C). Grease a 9×13-inch baking dish with olive oil.
- In a large mixing bowl, combine the shredded chicken, broccoli, cauliflower, bell peppers, half of the cheese, heavy cream, garlic, Italian seasoning, salt, and pepper.
- Mix all the ingredients well until everything is evenly coated.
- Transfer the mixture to the greased baking dish, spreading it out evenly.
- Top the casserole with the remaining cheese.
- Bake in the preheated oven for 30-40 minutes, or until the cheese is bubbly and golden brown.
- Remove from the oven and let cool for a few minutes before serving.
Nutrition Information
Yield
6Serving Size
1Amount Per Serving Calories 352Total Fat 29gSaturated Fat 15gTrans Fat 1gUnsaturated Fat 12gCholesterol 106mgSodium 229mgCarbohydrates 6gFiber 2gSugar 3gProtein 18g
All Chicken Recipes.com, occasionally offers nutritional information for recipes contained on this site. This information is provided as a courtesy and is an estimate only. This information comes from online calculators. Although allchickenrecipes.com attempts to provide accurate nutritional information, these figures are only estimates.
Final Thoughts
This low carb chicken casserole is not only a delicious meal but also a wonderful way to bring family and friends together. With its comforting flavors and simplicity, it’s an excellent addition to any weeknight dinner rotation. Enjoy the process of making it, and feel free to get creative with your ingredients and flavors. Happy cooking!